Warfarin treatment of mice bearing autochthonous tumors: effect on spontaneous metastases.

نویسندگان

  • J J Ryan
  • A S Ketcham
  • H Wexler
چکیده

Long-term oral administration of sodium warfarin significantly reduced the incidence of spontaneous metastases in the lungs from 83 percent in controls to 8 percent in treated C57/BL/6N mice. The size and weight of primary tumors in mice treated with warfarin were less than in control mice. Length of survival was unaffected.

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عنوان ژورنال:
  • Science

دوره 162 3861  شماره 

صفحات  -

تاریخ انتشار 1968